Dapsone: Difference between revisions
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| + | == Background == |
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| + | == Dosing == |
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| + | * '''Dermatitis herpetiformis:''' Start at 50 mg PO daily, increase to 300 mg daily, or higher to achieve full control, reduce to minimum maintenance dosage as soon as possible |
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| + | * '''PJP prophylaxis (primary or secondary):''' |
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| + | ** 100 mg PO once daily or in 2 divided doses as monotherapy |
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| + | ** Continue until CD4 count >200 cells/mm3 for >3 months |
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| + | * '''PJP treatment:''' 100 mg PO once daily in combination with [[trimethoprim]] for 21 days |
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[[Category:Antibiotics]] |
[[Category:Antibiotics]] |
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Revision as of 09:11, 3 March 2021
Background
- Diamino-diphenyl sulfone
Indications
- Second-line PJP prophylaxis (CD4 <200)
- Rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae
Dosing
- Dermatitis herpetiformis: Start at 50 mg PO daily, increase to 300 mg daily, or higher to achieve full control, reduce to minimum maintenance dosage as soon as possible
- PJP prophylaxis (primary or secondary):
- 100 mg PO once daily or in 2 divided doses as monotherapy
- Continue until CD4 count >200 cells/mm3 for >3 months
- PJP treatment: 100 mg PO once daily in combination with trimethoprim for 21 days
