Dalbavancin

From IDWiki

Background

  • Glycopeptide antibiotic, similar to vancomycin
  • Indicated for acute bacterial skin and skin structure infections in adults, but is being used off-label for osteomyelitis and infective endocarditis
  • Spectrum includes gram-positive cocci, including MRSA
  • Costs about CAD3000 per dose (CAD1000 per 500 mg vial)

Dosing

  • ABSSSI:
    • 1500 mg IV once, or
    • 1000 mg IV followed by 500 mg IV 1 week later