Cushing syndrome

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Background

  • Syndrome characterized by high serum cortisol levels

Etiologies

  • Exogenous cortisol from therapeutic corticosteroid use
  • ACTH-secreting pituitary adenoma
  • Cortisol-secreting adrenal adenoma, carcinoma, or hyperplasia
  • Paraneoplastic secretion of ACTH by a tumour