Cerebrospinal fluid leak: Difference between revisions

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==Background==
 
==Background==
  +
* CSF leaks are associated with a high risk of meningitis (10-25%, depending on etiology and chronicity)
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*CSF leaks are associated with a high risk of meningitis (10-25%, depending on etiology and chronicity)
  +
*May be spontaneous, traumatic, or post-neurosurgical
   
 
==Management==
 
==Management==
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* Current IDSA guidelines recommend:
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*Current IDSA guidelines[[CiteRef::tunkel201720]] recommend:
** No routine prophylactic antibiotic in patients with basilar skull fractures and CSF leak
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**No routine prophylactic antibiotic in patients with basilar skull fractures and CSF leak
** Surgical repair if leak lasts more than 7 days
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**Surgical repair if leak lasts more than 7 days
** Pneumococcal vaccination
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**Pneumococcal vaccination
   
 
==Further Reading==
 
==Further Reading==
  +
* Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. ''Clin Infect Dis''. 2017;64(6):e34-e65. doi: [https://doi.org/10.1093/cid/ciw861 10.1093/cid/ciw861]
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*Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. ''Clin Infect Dis''. 2017;64(6):e34-e65. doi: [https://doi.org/10.1093/cid/ciw861 10.1093/cid/ciw861]
   
 
[[Category:CNS infections]]
 
[[Category:CNS infections]]

Revision as of 19:41, 19 October 2020

Background

  • CSF leaks are associated with a high risk of meningitis (10-25%, depending on etiology and chronicity)
  • May be spontaneous, traumatic, or post-neurosurgical

Management

  • Current IDSA guidelines1 recommend:
    • No routine prophylactic antibiotic in patients with basilar skull fractures and CSF leak
    • Surgical repair if leak lasts more than 7 days
    • Pneumococcal vaccination

Further Reading

  • Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis. Clin Infect Dis. 2017;64(6):e34-e65. doi: 10.1093/cid/ciw861

References

  1. ^  Allan R. Tunkel, Rodrigo Hasbun, Adarsh Bhimraj, Karin Byers, Sheldon L. Kaplan, W. Michael Scheld, Diederik van de Beek, Thomas P. Bleck, Hugh J.L. Garton, Joseph R. Zunt. 2017 Infectious Diseases Society of America’s Clinical Practice Guidelines for Healthcare-Associated Ventriculitis and Meningitis*. Clinical Infectious Diseases. 2017;64(6):e34-e65. doi:10.1093/cid/ciw861.