Burkholderia cepacia
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Burkholderia cepacia complex /
Revision as of 11:17, 15 August 2020 by Aidan (talk | contribs) (Created page with "== Background == * Stain::Gram-negative Cellular shape::bacillus * Multiple mechanisms of resistance: ** β-lactamases ** RND efflux pumps ** Altered LPS conferring p...")
Background
- Gram-negative bacillus
- Multiple mechanisms of resistance:
- β-lactamases
- RND efflux pumps
- Altered LPS conferring polymixin resistance
- Gyrase mutations conferring fluoroquinolone resistance
Management
- Should be guided by antimicrobial susceptibility testing
- Antibiotic options include:
- TMP-SMX (preferred, if susceptible)
- Ceftazidime and ceftazidime-avibactam
- Meropenem and imipenem
- Minocycline
