Bortezomib: Difference between revisions
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* [[Proteasome inhibitor]] |
* [[Proteasome inhibitor]] |
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* Used for [[multiple myeloma]] and [[mantle cell lymphoma]] |
* Used for [[multiple myeloma]] and [[mantle cell lymphoma]] |
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| + | * Effects on immune system include neutropenia, lymphopenia (particularly CD8 T-cells and NK cells), dendritic cell inhibition, altered cytokine secretion |
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| + | * Increases risk of [[HSV]] and [[VZV]]; often used with concurrent [[dexamethasone]] |
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[[Category:Medications]] |
[[Category:Medications]] |
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Latest revision as of 13:05, 14 November 2022
- Proteasome inhibitor
- Used for multiple myeloma and mantle cell lymphoma
- Effects on immune system include neutropenia, lymphopenia (particularly CD8 T-cells and NK cells), dendritic cell inhibition, altered cytokine secretion
- Increases risk of HSV and VZV; often used with concurrent dexamethasone
