Bony metastases: Difference between revisions
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== Differential Diagnosis == |
== Differential Diagnosis == |
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− | * Osteoblastic lesions |
+ | * Osteoblastic (sclerotic) lesions, with deposition of new bone |
− | ** |
+ | **[[Prostate cancer]] |
− | ** Carcinoid |
+ | ** [[Carcinoid tumour]] |
− | ** Small cell lung cancer |
+ | ** [[Small cell lung cancer]] |
− | ** Hodgkin lymphoma |
+ | ** [[Hodgkin lymphoma]] |
+ | ** [[Medulloblastoma]] |
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− | * Osteolytic lesions |
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+ | * Osteolytic lesions, with destruction of normal bone |
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− | ** |
+ | **[[Renal cell carcinoma]] |
− | ** Melanoma |
+ | ** [[Melanoma]] |
− | ** Multiple myeloma |
+ | ** [[Multiple myeloma]] |
− | ** Thyroid cancer |
+ | ** [[Thyroid cancer]] |
− | ** Non-Hodgkin lymphoma |
+ | ** [[Non-Hodgkin lymphoma]] |
+ | ** [[Non-small cell lung cancer]] |
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+ | ** [[Langerhans cell histiocytosis]] |
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+ | ** [[Lytic bone lesion|Non-malignant causes of lytic bone lesions]] |
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* Mixed lesions |
* Mixed lesions |
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− | ** |
+ | **[[Breast cancer]], though it is predominantly osteolytic |
− | ** Colorectal and other gastrointestinal cancers |
+ | ** [[Colorectal cancer]] and other gastrointestinal cancers |
− | ** Squamous cell |
+ | ** [[Squamous cell cancer]] |
== Management == |
== Management == |
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− | * Denosumab at high dose |
+ | * [[Denosumab]] at high dose |
+ | * [[Bisphosphonate]] |
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− | * Bisphosphonates |
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+ | |||
+ | == Further Reading == |
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+ | |||
+ | * Bone Metastases: An Overview. ''Oncol Rev''. 2017 Mar 3; 11(1): 321. doi: [https://doi.org/10.4081/oncol.2017.321 10.4081/oncol.2017.321] |
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[[Category:Oncology]] |
[[Category:Oncology]] |
Latest revision as of 16:25, 18 May 2023
Differential Diagnosis
- Osteoblastic (sclerotic) lesions, with deposition of new bone
- Osteolytic lesions, with destruction of normal bone
- Mixed lesions
- Breast cancer, though it is predominantly osteolytic
- Colorectal cancer and other gastrointestinal cancers
- Squamous cell cancer
Management
- Denosumab at high dose
- Bisphosphonate
Further Reading
- Bone Metastases: An Overview. Oncol Rev. 2017 Mar 3; 11(1): 321. doi: 10.4081/oncol.2017.321