Bony metastases: Difference between revisions

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== Differential Diagnosis ==
 
== Differential Diagnosis ==
   
* Osteoblastic lesions
+
* Osteoblastic (sclerotic) lesions, with deposition of new bone
** Prostate cancer
+
**[[Prostate cancer]]
** Carcinoid tumours
+
** [[Carcinoid tumour]]
** Small cell lung cancer
+
** [[Small cell lung cancer]]
** Hodgkin lymphoma
+
** [[Hodgkin lymphoma]]
  +
** [[Medulloblastoma]]
* Osteolytic lesions
 
  +
* Osteolytic lesions, with destruction of normal bone
** Renal cell carcinoma
+
**[[Renal cell carcinoma]]
** Melanoma
+
** [[Melanoma]]
** Multiple myeloma
+
** [[Multiple myeloma]]
** Thyroid cancer
+
** [[Thyroid cancer]]
** Non-Hodgkin lymphoma
+
** [[Non-Hodgkin lymphoma]]
  +
** [[Non-small cell lung cancer]]
  +
** [[Langerhans cell histiocytosis]]
  +
** [[Lytic bone lesion|Non-malignant causes of lytic bone lesions]]
 
* Mixed lesions
 
* Mixed lesions
** Breast cancer
+
**[[Breast cancer]], though it is predominantly osteolytic
** Colorectal and other gastrointestinal cancers
+
** [[Colorectal cancer]] and other gastrointestinal cancers
** Squamous cell cancers
+
** [[Squamous cell cancer]]
   
 
== Management ==
 
== Management ==
   
* Denosumab at high dose
+
* [[Denosumab]] at high dose
  +
* [[Bisphosphonate]]
* Bisphosphonates
 
  +
  +
== Further Reading ==
  +
  +
* Bone Metastases: An Overview. ''Oncol Rev''. 2017 Mar 3; 11(1): 321. doi: [https://doi.org/10.4081/oncol.2017.321 10.4081/oncol.2017.321]
   
 
[[Category:Oncology]]
 
[[Category:Oncology]]

Latest revision as of 16:25, 18 May 2023

Differential Diagnosis

Management

Further Reading