Acute retinal necrosis: Difference between revisions

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(Created page with "== Background == * Definition: ** Well-demarcated retinal necrosis on peripheral retina ** Rapid progression of necrosis ** Circumferential spread ** Occlusive vasculopathy **...")
 
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** Vitreal and aqueous inflammation
 
** Vitreal and aqueous inflammation
   
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== Differential Diagnosis
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== Differential Diagnosis ==
 
* Most commonly [[HSV]] and [[VZV]], though [[CMV]] also possible
 
* Most commonly [[HSV]] and [[VZV]], though [[CMV]] also possible
   

Revision as of 10:47, 12 August 2020

Background

  • Definition:
    • Well-demarcated retinal necrosis on peripheral retina
    • Rapid progression of necrosis
    • Circumferential spread
    • Occlusive vasculopathy
    • Vitreal and aqueous inflammation

Differential Diagnosis

  • Most commonly HSV and VZV, though CMV also possible

Clinical Manifestations

  • Starts as anterior uveitis (painful, red eye with vision loss) that progresses to retinal necrosis
  • High rates of retinal detachment and blindness

Management

  • Directed by causative organism
  • Involvement of Ophthalmology
  • Typically requires intravenous ± intravitreal acyclovir, stepped down to oral valacyclovir
  • May require steroids
  • May require vitrectomy or laser therapy