Actinomyces: Difference between revisions

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Actinomyces
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= Actinomyces =
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= Microbiology =
 
== Microbiology ==
 
   
 
* Weakly Gram-positive bacterium that looks fungal under microscopy
 
* Weakly Gram-positive bacterium that looks fungal under microscopy
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* Spreads by direct invasion through tissue and creating fistulae
 
* Spreads by direct invasion through tissue and creating fistulae
   
== Syndromes ==
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= Syndromes =
   
=== Cervicofacial actinomycosis ===
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== Cervicofacial actinomycosis ==
   
 
* "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
 
* "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
 
* Most common form, accounting for ~50% of cases
 
* Most common form, accounting for ~50% of cases
   
=== Abdominal actinomycosis ===
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== Abdominal actinomycosis ==
   
 
* Presents as an abdominal mass that fistulizes to skin
 
* Presents as an abdominal mass that fistulizes to skin
   
=== Pulmonary actinomycosis ===
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== Pulmonary actinomycosis ==
   
 
* Presents as a chronic, non-resolving pneumonia or as a lung cancer
 
* Presents as a chronic, non-resolving pneumonia or as a lung cancer
 
* Can spread directly to involve heart as well
 
* Can spread directly to involve heart as well
   
=== Others ===
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== Others ==
   
 
* Endocarditis
 
* Endocarditis
   
== Management ==
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= Management =
   
 
* IV penicillin x4-6 weeks then PO penicillin x6-12 months
 
* IV penicillin x4-6 weeks then PO penicillin x6-12 months
 
* Alternatives include ceftriaxone, amox/clav
 
* Alternatives include ceftriaxone, amox/clav
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{{DISPLAYTITLE:''Actinomyces'' species}}
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[[Category:Bacteria]]

Revision as of 18:42, 14 August 2019

Microbiology

  • Weakly Gram-positive bacterium that looks fungal under microscopy
  • Oral and gut flora
  • Spreads by direct invasion through tissue and creating fistulae

Syndromes

Cervicofacial actinomycosis

  • "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
  • Most common form, accounting for ~50% of cases

Abdominal actinomycosis

  • Presents as an abdominal mass that fistulizes to skin

Pulmonary actinomycosis

  • Presents as a chronic, non-resolving pneumonia or as a lung cancer
  • Can spread directly to involve heart as well

Others

  • Endocarditis

Management

  • IV penicillin x4-6 weeks then PO penicillin x6-12 months
  • Alternatives include ceftriaxone, amox/clav