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- 15:12, 4 August 2022 Aidan talk contribs created page Autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy (Created page with "== Background == * Autosomal recessive genetic syndrome resulting from mutation of the ''AIRE'' gene == Clinical Manifestations == * Onset usually in the first 10 to 20 years of life * Hypoparathyroidism is the most common endocrine finding ** Addison disease, and ovarian failure are the next most common endocrine disorders ** Can also have diabetes mellitus and hypothyroidism * Alopecia is common, as well as tooth enamel hypoplasia, nail dystrophy...") Tag: Visual edit