- T-cell costimulation inhibitor
- Formed of extracellular domain of the cytotoxic T lymphocyte-associated antigen 4 linked to the Fc portion of human IgG1
- Decreases T cell activation
- Indications include RA and JRA
- Infectious complications include upper respiratory tract infections, and reports of pneumonia, sepsis, aspergillosis, sinusitis, candidiasis, bronchitis, cellulitis, HSV, and VZV
