Efalizumab

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CD 11a inhibitor
Monoclonal IgG1 antibody against the α subunit (CD 11a) of LFA-1
- Affects T cell activation, transfer from circulation to sites of inflammation in the skin, and T cell reactivation in the skin
Indications include psoriasis
Infectious complications include upper respiratory tract infections, gastroenteritis, and HSV

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Monoclonal antibodies