Bony metastases

Differential Diagnosis

• Osteoblastic lesions
  • Prostate cancer
  • Carcinoid tumour
  • Small cell lung cancer
  • Hodgkin lymphoma
• Osteolytic lesions
  • Renal cell carcinoma
  • Melanoma
  • Multiple myeloma
  • Thyroid cancer
  • Non-Hodgkin lymphoma
• Mixed lesions
  • Breast cancer
  • Colorectal cancer and other gastrointestinal cancers
  • Squamous cell cancer

Management

• Denosumab at high dose
• Bisphosphonate