Distribution
- Distribution into various body compartments depends on the fluid used
|
5% dextrose
|
0.9% NaCl
|
Colloids
|
Intracellular
|
667 mL
|
|
|
Extracellular
|
Interstitial
|
250 mL
|
750 mL
|
|
Intravascular
|
83 mL
|
25 mL
|
1000 mL
|
Crystalloids
Colloids
- Starches: BAD, increase mortality
- Gelatin and dextran: not available in Canada, and poor data
- Albumin:
- No difference when compared head-to-head as initial resuscitation fluid compared to crystalloid
- Very expensive, and is a blood product
- Products also contain sodium 110-140 mmol/L