Nitroglycerine

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Dosing

Heart Failure

  • Nitroglycerin 10 to 20 mcg/min IV infusion, increase by 5 to 10 mcg/min every 3 to 5 minutes as blood pressure tolerates
    • Maximum dose 200 mcg/min
  • Nitroglycerin 400 mcg translingual every 5 to 10 minutes
  • Monitor blood pressure and decrease dose if SBP <90 mmHg
  • Tolerance develops within 24 to 48 hours, so should only be used for short-term therapy