Posaconazole
From IDWiki
Therapeutic Drug Monitoring
- Measure trough 7 days after starting or adjusting dose, or adjusting interacting medications, or concerns of poor adherence or absorption
- For prophylaxis, target trough >0.7 mg/L, or random level 0.35 mg/L 48 h after starting therapy
- For treatment, target trough >1 mg/L
Epidemiologic Cutoff Values
| Species | ECV (mcg/mL) |
|---|---|
| C. albicans | 0.06 |
| C. glabrata | 2 |
| C. parapsilosis | 0.25 |
| C. tropicalis | 0.12 |
| C. krusei | 0.5 |
| C. lusitaniae | 0.12 |
| C. guilliermondii | 0.5 |
| C. kefyr | 0.25 |
