Genital ulcer disease
From IDWiki
Differential Diagnosis
Sexually-Transmitted Infections
| Organism | Disease | % | Incubation | Treatment |
|---|---|---|---|---|
| Painless | ||||
| Treponema pallidum pallidum | primary syphilis | 1% | 3-90 days | penicillin 2.4 MU IM once |
| Chlamydia trachomatis serovars L1-L3 | lymphogranuloma venereum | <1% | 3-30 days | doxycycline 100 mg PO bid for 21 days |
| Painful | ||||
| Herpes simplex virus | genital herpes | 95% | 2-7 days (1º) | acyclovir or valacyclovir for 5 to 10 days |
| Haemophilus ducreyi | chancroid | <1% | 5-14 days | ciprofloxacin 500 mg PO once |
| Klebsiella granulomatis | donovanosis (granuloma inguinale) | <1% | 1-180 days | azithromycin 1 g PO weekly for 21 days (and healed) |
Other Infectious Causes
Non-Infectious Causes
- Bullous dermatoses
- Non-autoimmune
- Contact dermatitis
- Erythema multiforme (usually secondary to HSV)
- Toxic epidermolysis
- Autoimmune
- Non-autoimmune
- Non-bullous dermatoses
- Malignancy
- Trauma
- Idiopathic (12-51%)
Further Reading
- Management and treatment of specific syndromes – Genital Ulcer Disease (GUD). Canadian Guidelines on Sexually Transmitted Infections. 2016.
