Faine's criteria
From IDWiki
Criteria
| Item | Points |
|---|---|
| Part A: Clinical Data | |
| Headache | 2 |
| Fever | 2 |
| Fever >39ºC | 2 |
| Conjunctival suffusion | 4 |
| Meningism | 4 |
| Myalgia | 4 |
| Conjunctival suffusion, meningism, and myalgia | 10 |
| Jaundice | 1 |
| Albuminuria or nitrogen retention | 2 |
| Hemoptysis or dyspnea | 2 |
| Part B: Epidemiological Factors | |
| Rainfall | 5 |
| Contact with contaminated environement | 4 |
| Animal contact | 1 |
| Part C: Bacteriological and Laboratory Findings | |
| Isolation of Leptospira in culture | diagnosis certain |
| Positive PCR | 25 |
| Positive ELISA IgM | 15 |
| Positive SAT | 15 |
| Other rapid serologic test | 15 |
| MAT positive once with high titre | 15 |
| MAT acute and convalescent with rising titre | 25 |
- Rapid serologic tests include latex agglutination, Leptodipstick, LeptoTek lateral flow, Lepto Tek Dri Dot
- Only one serologic test should be counted
Interpretation
- Parts A and B ≥26: presumptive diagnosis
- Parts A, B, and C ≥25: presumptive diagnosis
- Parts A, B, and C of 20 to 25: possible diagnosis
Further Reading
- Utility of modified Faine's criteria in diagnosis of leptospirosis. BMC Infect Dis. 2016;16:446 doi: 10.1186/s12879-016-1791-9
