Antifungal spectrum

Organism	AmB	Fluc	Itra	Vori	Posa	Anidula	Caspo	Mica	Flucyt
Aspergillus spp.	+	–	+	+	+	+	+	+	–
A. flavus	±	–	+	+	+	+	+	+	–
A. fumigatus	+	–	+	+	+	+	+	+	–
A. terreus	–	–	+	+	+	+	+	+	–
A. niger	+	–	±	+	+	+	+	+	–
Candida spp.	+	+	+	+	+	+	+	+	+
C. albicans	+	+	+	+	+	+	+	+	+
C. glabrata	+	±	±	+	+	+	+	+	+
C. krusei	+	–	±	+	+	+	+	+	±
C. lusitaniae	–	+	+	+	+	+	+	+	+
C. parapsilosis	+	+	+	+	+	±	±	±	+
C. tropicalis	+	+	+	+	+	+	+	+	+
Cryptococcus neoformans	+	+	+	+	+	–	–	–	+
Coccidioides spp.	+	+	+	+	+	±	±	±	–
Blastomyces	+	+	+	+	+	±	±	±	–
Histoplasma spp.	+	+	+	+	+	±	±	±	–
Fusarium spp.	±	–	–	+	+	–	–	–	–
Scedosporium apiospermum	±	–	±	+	+	–	–	–	–
Scedosporium prolificans	–	–	–	±	±	–	–	–	–
Zygomycetes	±	–	–	–	+	–	–	–	–

Aspergillus ustus is resistant to azoles and echinocandins, and variable resistance to amphotericin (though still susceptible to terbinafine)

Antifungal spectrum of activity