Congenital parvovirus

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Background

Trimester Transmission to Fetus
first 33%
second
third 0%
overall 9%

Clinical Presentation

  • Hydrops fetalis in utero
  • Heart failure
  • Myocarditis

Diagnosis

Serology

  • IgM antibody is detectable by 10 to 12 days after infection (peak viremia), and persists for up to 3 months
  • IgG antibody is detectable about 2 weeks after infection and persists for life
IgM IgG Interpretation
Susceptible
+ Acute infection
+ Remote infection, at least 3-4 months ago
+ + Recent infection, within 2-3 months