Actinomyces species

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Actinomyces /
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Microbiology

  • Weakly Gram-positive bacterium that looks fungal under microscopy
  • Oral and gut flora
  • Spreads by direct invasion through tissue and creating fistulae

Syndromes

Cervicofacial actinomycosis

  • "Lumpy jaw syndrome" with painless jaw mass, trismus, and eventually pain
  • Most common form, accounting for ~50% of cases

Abdominal actinomycosis

  • Presents as an abdominal mass that fistulizes to skin

Pulmonary actinomycosis

  • Presents as a chronic, non-resolving pneumonia or as a lung cancer
  • Can spread directly to involve heart as well

Others

  • Endocarditis

Management

  • IV penicillin x4-6 weeks then PO penicillin x6-12 months
  • Alternatives include ceftriaxone, amox/clav