Non-gonococcal urethritis

Differential Diagnosis

• Bacterial
  • Chlamydia trachomatis (20-40%), which is the second-most common cause of urethritis after Neisseria gonorrhoeae
  • Mycoplasma genitalium (20-30%)
  • Ureaplasma urealyticum
• Parasitic
  • Trichomonas vaginalis
• Viral
  • Herpes simplex virus
  • Adenovirus
• Fungal
  • Candida albicans
• Idiopathic in up to 50%

Investigations

• In general, first void urine is preferred to mid-stream urine for urethral pathogens