Ceftobiprole

From IDWiki

Revision as of 10:37, 3 September 2020 by Aidan (talk | contribs) (Created page with "== Background == === Mechanism of Action === * Binds to and inhibits PBP-2a on MRSA * Binds to and inhibits PBP-2x on penicillin-resistant Streptococcus pneumoniae ===...")

(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)

Jump to:navigation, search

Background

Mechanism of Action

Binds to and inhibits PBP-2a on MRSA
Binds to and inhibits PBP-2x on penicillin-resistant Streptococcus pneumoniae

Spectrum of Activity

Active against MRSA, ampicillin-susceptible Enterococcus, and penicillin-resistant Streptococcus pneumoniae, as well as aerobic Gram-negative bacteria similar to other third-generation cephalosporins
Not active against Pseudomonas, ESBL-producers, or AmpC-producers

Dosing

Ceftobiprole 500 mg IV q8h over 2 hours

Safety

Adverse Drug Reactions

Nausea, diarrhea, neutropenia (4%), dysgeusia

Retrieved from "https://idwiki.org/index.php?title=Ceftobiprole&oldid=6584"

Cephalosporins