Bacterial meningitis (IDSA 2004)
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Bacterial meningitis (IDSA 2004)
Table 4: Empiric Treatment
| Population | Common pathogens | Antimicrobial therapy |
|---|---|---|
| Age | ||
| <1 month | GBS, E.coli, Listeria, Klebsiella | amp + cefotax, or amp + AG |
| 1-23 months | S.pneumo, N.mening, GBS, H.flu, E.coli | vanco + 3G ceph |
| 2-50 years | N.mening, S.pneumo | vanco + 3G ceph |
| >50 years | S.pneumo, N.mining, Listeria, GNBs | vanco + 3G ceph + amp |
| Head trauma | ||
| Basilar skull fracture | S.pneumo, H.flu, GAS | vanco + 3G ceph |
| Penetrating trauma | Staph.aureus, CoNS, GNBs | vanco + cefep, or vanco + ceftaz, or vanco + mero |
| Post-neurosurgery | GNBs, Staph.aureus, CoNS | vanco + cefep, or vanco + ceftaz, or vanco + mero |
| CSF shunt | CoNS, Staph,aureus, GNBs, P.acnes | vanco + cefep, or vanco + ceftaz, or vanco + mero |
