Tissue penetration of antimicrobials
From IDWiki
| Class | Antimicrobial | Blood | CNS | Urine |
|---|---|---|---|---|
| Penicillins | β-lactamase inhibitors | NO | ||
| Cephalosporins | First- and second-generation cephalosporins | NO | ||
| Cephamycins | NO | |||
| Carbapenems | ||||
| Lincosamides | clindamycin | NO | ||
| Fluoroquinolones | NO? | |||
| Macrolides | NO | |||
| Tetracyclines | NO |
References
- ^ Cornelia B. Landersdorfer, Jürgen B. Bulitta, Martina Kinzig, Ulrike Holzgrabe, Fritz Sörgel. Penetration of Antibacterials into Bone. Clinical Pharmacokinetics. 2009;48(2):89-124. doi:10.2165/00003088-200948020-00002.
- ^ L. Brockhaus, D. Goldblum, L. Eggenschwiler, S. Zimmerli, C. Marzolini. Revisiting systemic treatment of bacterial endophthalmitis: a review of intravitreal penetration of systemic antibiotics. Clinical Microbiology and Infection. 2019;25(11):1364-1369. doi:10.1016/j.cmi.2019.01.017.
