Immunization of people with asplenia and hyposplenia

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Revision as of 19:11, 15 August 2020 by Aidan (talk | contribs)
  • Can receive all routine vaccines, including live vaccines
  • Try to complete vaccines at least 2 weeks before splenectomy, or wait at least 2 weeks after vaccination to start
  • Vaccines specifically recommended in asplenia or hyposplenia:
    • Haemophilus influenzae type b (Hib), one dose
    • Neisseria meningitidis:
      • Quadrivalent Men-C-ACYW-135, two doses 8 weeks apart
      • 4CMenB, two doses 4 weeks apart
    • Streptococcus pneumoniae: Pneu-C-13, one dose, followed in 8 weeks by Pneu-P-23, one dose
    • Influenza (annually)
    • If transfusion-dependent: hepatitis A and B vaccines
  • Should also have pill-in-pocket broad-spectrum oral antibiotics to be taken in case of fever
Sample schedule for vaccination before planned splenectomy
Week -10 Week -2 Week 0
Men-C-ACYW-135

4CMenB Pneu-C-13 Hib

Men-C-ACYW-135

4CMenB Pneu-P-23

splenectomy
influenza, if appropriate season