Maribavir

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  • Class is benzimidazole riboside
  • Mechanism of action is inhibition of UL97-mediated phosphorylation of nuclear lamin A/C
  • Main indication is CMV prophylaxis in solid organ transplant

Further Reading

  • Maribavir for Refractory or Resistant Cytomegalovirus Infections in Hematopoietic-cell or Solid organ Transplant Recipients: A Randomized, Dose-ranging, Double-blind, Phase 2 Study. Clin Infect Dis. 2019;68(8):1255–1264. DOI: 10.1093/cid/ciy706
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