Background
Mechanism of Action
- Inhibits viral neuraminidase
Dose
Adults
- Influenza (treatment): 75 mg PO bid
- Influenza (prophylaxis): 75 mg PO daily
Renal Dosing
| Indication | CrCl >60 | CrCl >30 to 60 mL/min | CrCl >10 to 30 mL/min | IHD |
|---|---|---|---|---|
| Influenza (treatment) | Usual dose | 30 mg PO bid | 30 mg PO daily | 30 (low-flux) to 75 (high-flux) mg PO after dialysis |
| Influenza (prophylaxis) | Usual dose | 30 mg PO daily | 30 mg PO every other day | 30 mg PO after every other dialysis |
