Nutritionally variant streptococci

Background

• Require pyridoxine (vitamin B6) supplementation to group
• Also called pyridoxal-dependent or stalliting streptococci

Organisms

• Abiotrophia defectiva
• Granulicatella adiacens
• Granulicatella elegans
• Granulicatella para-adiacens

Clinical Manifestations

• Subacute bacterial endocarditis is the most well-known disease association