Hypertensive crisis

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Definition

  • Emergency if BP >180/120 associated with new or worsening target organ damage
  • Urgency if stable without target organ damage; they can be managed as outpatients

Management

Acute Care

Target

  • If aortic dissection, severe preeclampsia, pheo crisis: lower to <140 within the first hour
    • Or to <120 for aortic dissection
  • Otherwise: decrease by no more than 25% in first hour, then to 160/100 over the next 6 hours, then to normal over next day

Pharmacotherapy

  • Labetalol
    • Preferred for aortic dissection and acute MI
  • Sodium nitroprusside or nitroglycerin
  • Hydralazine
  • Nicardipine and enalaprilat, if you can find them