Bony metastases

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Differential Diagnosis

  • Osteoblastic lesions
    • Prostate cancer
    • Carcinoid tumours
    • Small cell lung cancer
    • Hodgkin lymphoma
  • Osteolytic lesions
    • Renal cell carcinoma
    • Melanoma
    • Multiple myeloma
    • Thyroid cancer
    • Non-Hodgkin lymphoma
  • Mixed lesions
    • Breast cancer
    • Colorectal and other gastrointestinal cancers
    • Squamous cell cancers

Management

  • Denosumab at high dose
  • Bisphosphonates