Behçet disease

Definition

• Idiopathic inflammatory disorder characterized by pathergy and recurrent oral and genital ulcers

International Criteria for Behçet's Disease

• Recurrent oral ulcerations (aphthous or herpetiform) at least 3 times in a year
• And any two of the following:
  • Recurrent genital lesions
  • Uveitis or retinal vasculitis
  • Skin lesions
    • Erythema nodosum
    • Pseudofolliculitis
    • Papulopustular lesions
    • Acneiform nodules
  • Positive pathergy test
    • 20G needle inserted into skin, area circled with a pen
    • Reassess at 24 and 48 hours for a papule
    • Most common in Mediterranean patients