Balamuthia mandrillaris

From IDWiki
Balamuthia mandrillaris /
Revision as of 23:51, 3 June 2020 by Aidan (talk | contribs)

Background

Microbiology

Epidemiology

  • Present in soil
  • More common in US and South America
  • More common in Hispanics

Clinical Presentation

  • Causes granulomatous amebic encephalitis (GAE) alone, skin lesions followed by GAE, or (rarely) skin lesions alone
  • GAE is characterized by progressive hemorrhagic necrosis of brain, with 90% mortality
  • Often preceded by skin lesions, typically affecting the nose and cheeks, that can progress over months
  • Difficult to treat, with high mortality