Southern tick-associated rash illness

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Southern tick-associated rash illness (STARI)

Microbiology

  • Unknown; although Borrelia lonestari has been proposed as the causative organism, this has not been confirmed

Epidemiology

  • Transmitted by the Lone star tick, Amblyomma americanum, with a presumed deer reservoir
  • Present in southern and south-east US

Clinical Presentation

  • Incubation period of 6 to 9 days
  • Erythema migrans, similar to Lyme disease

Coinfections

  • Human monocytic ehrlichiosis
  • Heartland virus
  • Q fever

Differential Diagnosis

  • Lyme disease

Management

  • Reasonable to treat similarly to Lyme disease
  • Doxycycline for 10 to 30 days, or amoxicillin, or cefuroxime
  • Longer treatment favoured for signs of disseminated disease