Colistin
From IDWiki
Resistance
- Conferred by alterations in lipid A, either reducing its charge or eliminating it altogether
- May be chromosomal (e.g. pmrC, pmrF, pmrAB, lpxA, lpxC, lpxD, OprH) or plasmid-mediated (e.g. mcr-1 gene)
- Often seen in Proteus, Providencia, Serratia, Morganella, Burkholderia cepacia, Neisseria, and Burcella
