Fonsecaea species

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Clinical Presentation

  • Most common agent causing human chromoblastomycosis
  • Infection likely occurs as a result of direct traumatic inoculation of plant debris into a wound i.e. coconut shells
  • Chronic localized fungal infection of the skin and subcutaneous tissue that produces raised, scaly lesions, usually in the lower extremities
  • Lesions are warty, cauliflower-like

Diagnosis

  • Culture
    • Microscopy:
    • Septate hyphae with poorly formed cylindrical conidiophores producing short chains of conidia
      • Pathognomonic muriform cells (copper penny) found on histology

Management

  • Surgery + itraconazole + terbinafine for severe cases has been suggested