Rickettsia conorii
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Rickettsia conorii /
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Boutonneuse fever (R. conorii)
- Rickettsia conorii is a tickborne rickettsial species that causes boutonneuse fever
Epidemiology
- Transmitted by Rhipicephalus sanguineus ticks
- Founds in India, Pakistan, Israel, Russia, Georgia, Bulgaria, Turkey, Ukraine, Ethiopia, Kenya, South Africa, Morocco, and southern Europe
Clinical Presentation
- Also known as Marseilles fever, Mediterranean spotted fever, Kenya tick typhus, Israeli tick typhus, Astrakhan spotted fever, and Indian tick typhus
- Often has an eschar at the site of tick bit innoculation ("tache noir"), but not always
- Petechial rash, GI symptoms, obtundation, tachypnea, hepatomegaly, leukocytosis, coagulopathy, AKI, bilirubin elevation, AST elevation, and CK elevation
- Procoagulant, and 10% develop DVT
- Can present as acute pancreatitis
- Can be quite severe with higher mortality than others in the spotted fever group
