Coagulase-negative staphylococci
From IDWiki
- Group of Gram-positive cocci that are catalase positive and coagulase negative
Organisms
- Staphylococcus epidermidis group
- Staphylococcus haemolyticus group
- Staphylococcus saprophyticus: mainly causes UTIs
- Staphylococcus massiliensis
- Staphylococcus lugdenensis: has more in common with Staphylococcus aureus and should never be considered a contaminant
- Unclear grouping
Clinical Manifestations
- Common contaminants of blood culture bottles
- Infections more commonly of indwelling hardware
- Endocarditis occasionally, and the highest risk is with Staphylococcus epidermidis than with other species1
Management
- Generally resistant to β-lactams
- First-line: vancomycin
- Alternatives: linezolid, daptomycin, co-trimoxazole, ciprofloxacin, doxycycline
References
- ^ Antonio Ramos-Martínez, Patricia González-Merino, Elena Suanzes-Martín, Marta Murga-de la Fuente, Gabriela Escudero-López, Ane Andrés-Eisenhofer, Esther Expósito-Palomo, Andrea Gutierrez-Villanueva, Itziar Diego-Yagüe, Elena Múñez, Ana Fernandez-Cruz, Jorge Calderón-Parra. Risk of endocarditis among patients with coagulase-negative Staphylococcus bacteremia. Scientific Reports. 2023;13(1). doi:10.1038/s41598-023-41888-7.
