Mycoplasma pneumoniae

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Mycoplasma pneumoniae /
Revision as of 15:29, 11 November 2024 by Aidan (talk | contribs) (Created page with "{{DISPLAYTITLE:''Mycoplasma pneumoniae''}} == Background == * Atypical bacterium within the genus Genus::Mycoplasma * Incidence fluctuates with epidemic years every 3 to 7 years and non-epidemic years mostly very low rates * More common in late summer and fall during epidemic years == Clinical Manifestations == * Most commonly causes subacute pneumoniae within influenza-like illness followed by persistent cough and malaise * Hematologic manifestations include...")
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Background

  • Atypical bacterium within the genus Mycoplasma
  • Incidence fluctuates with epidemic years every 3 to 7 years and non-epidemic years mostly very low rates
  • More common in late summer and fall during epidemic years

Clinical Manifestations

Diagnosis

  • PCR from NP swab
  • Serology can be helpful in making retrospective diagnosis

Investigations

  • CBC often shows a mild hemolytic anemia, with low hemoglobin and high bilirubin, LDH, and reticulocytes
    • Coombs and col-agglutinin titres aretypically positive though these tests are not usually needed
  • Normal to mildly elevated white count
  • Mild liver enzyme abnormalities
  • Chest x-ray shows reticulonodular or patchy opacities, bilaterally or unilaterally
    • Occasional small pleural effusions

Management

  • Mostly self-limited
  • When treated, usually treated with macrolides, tetracyclines or fluoroquinolones
    • Unclear amount of macrolide resistance in Canada