Interestingly, there is a phenomenon of increased direct bilirubin higher than total bilirubin in patients with plasma cell dyscrasia such as multiple myeloma, possibly due to interference from the elevated protein1
References
^Tareq Alyousef, Kumar Kunnal Batra, Harsha v Poola, Namrata Das Batra, Moushmi Shah, Shweta Gupta, Rose Catchatourian. A Phenomenon of Normal Total Bilirubin with Increased Direct Bilirubin Noted In Patients with Plasma Cell Dyscrasias. Blood. 2010;116(21):4986-4986. doi:10.1182/blood.v116.21.4986.4986.