Cryopyrin-associated periodic syndrome
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Revision as of 20:20, 12 July 2023 by Aidan (talk | contribs) (Created page with "== Background == * Mutation in NLRP3 gene * One of the periodic fever syndrome == Clinical Manifestations == * Three different clinical manifestations: ** Familial cold-associated syndrome (FCAS) *** Episodes of fever, rashes, arthralgias, usually triggered by exposure to cold ** Muckle-Wells syndrome (MWS) *** Episodes of fever, but with migrating urticaria-like lesions, ocular abnormalities, and progressive sensorineural deafness, and possibly amyloidosi...")
Background
- Mutation in NLRP3 gene
- One of the periodic fever syndrome
Clinical Manifestations
- Three different clinical manifestations:
- Familial cold-associated syndrome (FCAS)
- Episodes of fever, rashes, arthralgias, usually triggered by exposure to cold
- Muckle-Wells syndrome (MWS)
- Episodes of fever, but with migrating urticaria-like lesions, ocular abnormalities, and progressive sensorineural deafness, and possibly amyloidosis
- Chronic infantile neurological cutaneous articular syndrome (CINCA syndrome)
- Familial cold-associated syndrome (FCAS)
