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- 15:40, 27 June 2025 Aidan talk contribs created page Primary sclerosing cholangitis (Created page with "== Background == * Chronic disorder characterized by inflammation of the intra- and extra-hepatic bile ducts * Commonly comorbid with ulcerative colitis (about 70% of cases) * Possibly a hereditary component == Clinical Manifestations == * Often asymptomatic, with persistent ALP elevation * Fatigue, pruritus, jaundice * Increased risk of hepatocellular carcinoma == Investigations == * Anti-smooth muscle antibodies; may also have posi...") Tag: Visual edit