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- 16:00, 12 January 2023 Aidan talk contribs created page Primary biliary cholangitis (Created page with "==Clinical Manifestations== * Fatigue and pruritus * Jaundice * Hepatosplenomegaly ==Investigations== * ALP always elevated (often very high), ALT may be mildly elevated * Antimitochondrial antibodies are 95% sensitive * ANA elevated in about 70% ==Diagnosis== * No extrahepatic biliary obstruction, no comorbidities affecting the liver, and at least two of the following three criteria: ** ALP greater than 1.5 times the upper limit of normal ** Antimitochondrial antibody...")
