Fusarium solani

Background

• Lives in soil and plant debris worldwide
• Teleomorph is Nectria haematococca
• Fast grower
• White to cream mycelium, sometimes with later areas of green or blueish-brown
• Characteristic bean-shaped microconidia
• Biosafety level 2
• Produces ciclosporin A

Clinical Manifestations

• Most common infection in humans is keratitis, including with outbreaks from contact lenses
• Can also cause endophthalmitis, onychomycosis, cutaneous and subcutaneous infections, septic arthritis, mycetoma, and sinusitis
• In immunosuppressed hosts, can cause disseminated infections with very high mortality