Alcoholic hepatitis
From IDWiki
Revision as of 14:53, 19 February 2022 by Aidan (talk | contribs) (Created page with "== Management == * Supportive care including management for alcohol withdrawal, hydration, nutritional support * Calculate [https://www.mdcalc.com/maddreys-discriminant-f...")
Management
- Supportive care including management for alcohol withdrawal, hydration, nutritional support
- Calculate Maddrey discriminant function
- Consider glucocorticoids for Maddrey of 32 or higher
- Prednisolone 40 mg p.o. daily, preferred over prednisone
- Methylprednisolone 32 mg IV daily, as alternative
- Duration is 28 days followed by a 16 day taper (decrease by 10 mg every 4 days until 10 mg, then by 5 mg every 3 days)
- Stopped early if no biochemical response within the first week (either Maddrey score or bilirubin)
- For those who have an indication for glucocorticoids but who cannot receive them, pentoxifylline 400 mg p.o. tid
