Genital ulcer disease

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Differential Diagnosis

Sexually-Transmitted Infections

Organism Disease % Incubation Treatment
Herpes simplex virus genital herpes 95% 2-7 days (1º)
Treponema pallidum pallidum primary syphilis 1% 3-90 days penicillin 2.4 MU IM once
Haemophilus ducreyi chancroid <1% 5-14 days
Chlamydia trachomatis serovars L1-L3 lymphogranuloma venereum <1% 3-30 days doxycycline 100 mg PO bid for 21 days
Klebsiella granulomatis donovanosis (granuloma inguinale) <1% 1-180 days azithromycin 1 g PO weekly for 21 days (and healed)

Other Infectious Causes

Non-Infectious Causes

Further Reading