Vaccination after hematopoietic stem cell transplantation
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- Following hematopoietic stem cell transplantation, the new, naive immune system requires essentially all (allogeneic) or most (autologous) routine immunizations
- Most live vaccines can be given after 24 months, including univalent varicella, MMR, and yellow fever faccines
- MMRV, rotavirus, smallpox, oral poliovirus are all contraindicated
- Must not be experiencing graft-versus-host disease or undergoing significant immunosuppression
- No corticosteroids or other immunosuppressnats for at least 3 months
- Must also be assessed by their primary team as having normal immunity
- Close contacts should also ensure vaccinations are up to date