Neisseria meningitidis

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Neisseria meningitidis /
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Background

Microbiology

  • Gram-negative diplococcus
  • Traditionally organized by serogroups of capsular polysaccharide
    • A, B, C, E, H, I/K, L/ W, X, Y, and Z are confirmed genetically

Epidemiology

  • Six serogroups cause essentially all disease: A, B, C, W, X, and Y
  • In Canada, serogroups B, C, W-135 and Y are the most common causes, with B being the most commonly reported
    • Historically, B caused the majority of sporadic cases, and virulent serogroup C caused the majority of outbreaks