Bacterial meningitis (IDSA 2004)
From IDWiki
Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, Whitley RJ. Practice guidelines for the management of bacterial meningitis. Clin Infect Dis. 2004 Nov 1;39(9):1267-84. Epub 2004 Oct 6. doi: 10.1086/425368
Table 4: Empiric Treatment
| Population | Common pathogens | Antimicrobial therapy |
|---|---|---|
| Age | ||
| <1 month | GBS, E.coli, Listeria, Klebsiella | amp + cefotax, or amp + AG |
| 1-23 months | S.pneumo, N.mening, GBS, H.flu, E.coli | vanco + 3G ceph |
| 2-50 years | N.mening, S.pneumo | vanco + 3G ceph |
| >50 years | S.pneumo, N.mining, Listeria, GNBs | vanco + 3G ceph + amp |
| Head trauma | ||
| Basilar skull fracture | S.pneumo, H.flu, GAS | vanco + 3G ceph |
| Penetrating trauma | Staph.aureus, CoNS, GNBs | vanco + cefep, or vanco + ceftaz, or vanco + mero |
| Post-neurosurgery | GNBs, Staph.aureus, CoNS | vanco + cefep, or vanco + ceftaz, or vanco + mero |
| CSF shunt | CoNS, Staph,aureus, GNBs, P.acnes | vanco + cefep, or vanco + ceftaz, or vanco + mero |
