Post-transplant acute limbic encephalitis

From IDWiki
Revision as of 23:58, 10 February 2020 by Aidan (talk | contribs) (Created page with "* Limbic encephalitis syndrome following hematopoietic stem cell transplantation == Background == * Caused by HHV-6 == Clinical Presentation == * Onset 2 weeks to 2 mont...")
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
  • Limbic encephalitis syndrome following hematopoietic stem cell transplantation

Background

Clinical Presentation

  • Onset 2 weeks to 2 months after transplant
  • Presents with confusion, amnesia, hallucinations
  • Can cause seizures
  • Hyponatremia is common

Management

  • Treat seizures with antiepileptic medications
  • Treat any possible concomitant risk factors such as hyponytremia
  • Antivirals: acyclovir, ganciclovir, or foscarnet for 10 days to 4 weeks